Home » Pain Medicine » Maxalt (Rizatriptan)
Maxalt (Rizatriptan) is a headache medicine. It is believed to work by narrowing the blood vessels around the brain. It also reduces substances in the body that can trigger headache pain nausea sensitivity to light and sound and other migraine symptoms. Maxalt (Rizatriptan) will only treat a headache that has already begun. It will not prevent headaches or reduce the number of attacks.
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About Maxalt (Rizatriptan):
Product Type: Pain Medicine
Brand name: Maxalt
Generic name: Rizatriptan
What is Maxalt (Rizatriptan)?
Maxalt is a headache medicine. It is believed to work by narrowing the blood vessels around the brain. Maxalt also reduces substances in the body that can trigger headache pain nausea sensitivity to light and sound and other migraine symptoms.
Maxalt is used to treat migraine headaches.
Maxalt will only treat a headache that has already begun. It will not prevent headaches or reduce the number of attacks.
Maxalt may also be used for other purposes not listed in this medication guide.
What is the most important information I should know about rizatriptan?
Maxalt can cause serious side effects on the heart including heart attack or stroke. Although these side effects are rare do not use this medication if you have a history of heart disease angina (chest pain) blood circulation problems ischemic bowel disease severe or uncontrolled high blood pressure or history of a heart attack or stroke.
Before using rizatriptan tell your doctor if you have coronary artery disease or risk factors for coronary artery disease (such as diabetes menopause smoking being overweight having high blood pressure or high cholesterol having a family history of coronary artery disease being older than 40 and a man or being a woman who has had a hysterectomy).
Do not use rizatriptan if you have taken a monoamine oxidase inhibitor (MAOI) such as isocarboxazid (Marplan) tranylcypromine (Parnate) rasagiline (Azilect) selegiline (Eldepryl Emsam) or phenelzine (Nardil) in the past 14 days. Do not use rizatriptan within 24 hours after taking almotriptan (Axert) eletriptan (Relpax) frovatriptan (Frova) sumatriptan (Imitrex) naratriptan (Amerge) zolmitriptan (Zomig) or ergot medicine such as methysergide (Sansert) ergotamine (Ergomar Ergostat Cafergot Ercaf Wigraine) dihydroergotamine (D.H.E. 45 Migranal Nasal Spray) ergonovine (Ergotrate) methylergonovine (Methergine). Before taking rizatriptan tell your doctor if you are also taking an antidepressant such as citalopram (Celexa) duloxetine (Cymbalta) escitalopram (Lexapro) fluoxetine (Prozac Sarafem) fluvoxamine (Luvox) paroxetine (Paxil) sertraline (Zoloft) or venlafaxine (Effexor).
Maxalt will only treat a headache that has already begun. It will not prevent headaches or reduce the number of attacks.
After taking a rizatriptan tablet you must wait two (2) hours before taking a second tablet. Do not take more than 30 mg of rizatriptan in 24 hours.
What should I discuss with my healthcare provider before using rizatriptan?
Do not use this medication if you are allergic to rizatriptan or if you have:
• a history of heart disease angina (chest pain) blood circulation problems or history of a heart attack or stroke;
• ischemic bowel disease;
• severe or uncontrolled high blood pressure; or
• a headache that is not like other headaches you have had.
Do not use rizatriptan if you have taken a monoamine oxidase inhibitor (MAOI) such as isocarboxazid (Marplan) tranylcypromine (Parnate) rasagiline (Azilect) selegiline (Eldepryl Emsam) or phenelzine (Nardil) in the past 14 days. Do not use rizatriptan within 24 hours after taking any of the following medicines:
• almotriptan (Axert) eletriptan (Relpax) frovatriptan (Frova) sumatriptan (Imitrex) naratriptan (Amerge) or zolmitriptan (Zomig); or
• ergot medicine such as methysergide (Sansert) ergotamine (Ergomar Ergostat Cafergot Ercaf Wigraine) dihydroergotamine (D.H.E. 45 Migranal Nasal Spray) ergonovine (Ergotrate) methylergonovine (Methergine).
Before using rizatriptan tell your doctor if you have:
• high blood pressure;
• liver disease;
• kidney disease;
• phenylketonuria (tablets may contain phenylalanine);
• coronary artery disease (or risk factors that include diabetes menopause smoking being overweight having high blood pressure or high cholesterol having a family history of coronary artery disease being older than 40 and a man or being a woman who has had a hysterectomy).
If you have any of these conditions you may need a dose adjustment or special tests to safely take rizatriptan.
FDA pregnancy category C. This medication may be harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment.
Your name may need to be listed on a rizatriptan pregnancy registry when you start using this medication.
It is not known whether rizatriptan passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby. This medicine should not be given to anyone younger than 18 years old.
How should I use rizatriptan?
Take this medication exactly as it was prescribed for you. Do not take the medication in larger amounts or take it for longer than recommended by your doctor. Follow the instructions on your prescription label.
Take rizatriptan as soon as you notice headache symptoms or after an attack has already begun.
Your doctor may want to give your first dose of this medicine in a hospital or clinic setting to see if you have any serious side effects.
Take one rizatriptan tablet whole with a full glass of water.
To take rizatriptan orally disintegrating tablets (Maxalt-MLT):
• Keep the tablet in its blister pack until you are ready to take the medicine. Open the package and peel back the foil from the tablet blister. Do not push a tablet through the foil or you may damage the tablet.
• Using dry hands remove the tablet and place it in your mouth. It will begin to dissolve right away.
• Do not swallow the tablet whole. Allow it to dissolve in your mouth without chewing.
• Swallow several times as the tablet dissolves. If desired you may drink liquid to help swallow the dissolved tablet.
After taking a tablet: If your headache does not completely go away or goes away and comes back take a second tablet two (2) hours after the first. Do not take more than 30 mg of rizatriptan in 24 hours. If your symptoms have not improved contact your doctor before taking any more tablets.
Contact your doctor if you have more than four headaches in one month (30 days).
Store rizatriptan at room temperature away from moisture and heat.
What happens if I miss a dose?
Since rizatriptan is used as needed it does not have a daily dosing schedule. Call your doctor promptly if your symptoms do not improve after using rizatriptan.
After taking a rizatriptan tablet you must wait two (2) hours before taking a second tablet. Do not take more than 30 mg of rizatriptan in 24 hours.
What happens if I overdose?
Seek emergency medical attention if you think you have used too much of this medicine.
Overdose symptoms may include severe headache blurred vision trouble concentrating chest pain numbness seizure (convulsions) neck stiffness tiredness lack of coordination feeling light-headed or fainting.
What should I avoid while using rizatriptan?
Maxalt can cause side effects that may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be awake and alert.
Maxalt side effects
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face lips tongue or throat. Stop using rizatriptan and call your doctor at once if you have any of these serious side effects:
• chest pain or heavy feeling pain spreading to the arm or shoulder nausea sweating general ill feeling;
• sudden numbness or weakness especially on one side of the body;
• sudden headache confusion problems with vision speech or balance;
• fast heart rate agitation muscle stiffness hallucinations lack of coordination with nausea vomiting or diarrhea;
• sudden and severe stomach pain and bloody diarrhea; or
• numbness or tingling and a pale or blue-colored appearance in your fingers or toes.
Less serious side effects may include:
• dry mouth upset stomach;
• mild headache (not a migraine);
• feeling too warm or too cold;
• tremors confusion;
• warmth redness or tingling under your skin;
• feeling of pain or pressure in your neck and throat; or
• weakness dizziness sleepiness.
This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect.
What other drugs will affect rizatriptan?
Before using rizatriptan tell your doctor if you are using any of the following drugs:
• propranolol (Inderal InnoPran);
• an antidepressant such as citalopram (Celexa) duloxetine (Cymbalta) escitalopram (Lexapro) fluoxetine (Prozac Sarafem) fluvoxamine (Luvox) paroxetine (Paxil) sertraline (Zoloft) or venlafaxine (Effexor); or
• another migraine medicine such as almotriptan (Axert) eletriptan (Relpax) frovatriptan (Frova) sumatriptan (Imitrex) naratriptan (Amerge) or zolmitriptan (Zomig).
This list is not complete and there may be other drugs that can interact with rizatriptan. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins minerals herbal products and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.
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